{"data":{"type":"company_profile_ai","id":47827,"entity_id":"wefunder:company:47827","attributes":{"canonical_url":"https://wefunder.com/quadrant.biosciences","retrieval_urls":{"canonical":"https://wefunder.com/quadrant.biosciences","json":"https://wefunder.com/quadrant.biosciences.json","markdown":"https://wefunder.com/quadrant.biosciences.md","ai_json":"https://wefunder.com/quadrant.biosciences.ai.json","ai_text":"https://wefunder.com/quadrant.biosciences.ai.txt","changelog_json":"https://wefunder.com/quadrant.biosciences.changelog.json","schema":"https://wefunder.com/.well-known/ai-profile-schema.json"},"updated_at":"2026-06-15T05:00:18Z","generated_at":"2026-06-15T22:17:57Z","profile_visibility":{"owner_published":true,"public_search_results":true,"site_search_listed":true,"privacy_mode":"promote","invite_only":false},"company":{"id":47827,"entity_id":"wefunder:company:47827","slug":"quadrant.biosciences","name":"Quadrant Biosciences","tagline":"We develop novel, saliva based tests for Autism, COVID-19 and Parkinson's. ","elevator_pitch":"We develop\u0026nbsp;epigenetic saliva biomarkers including the world's first saliva test for autism. We recently received FDA emergency use authorization for a COVID-19 saliva test, and are currently working on developing tests for Parkinson's disease, concussion, and Anorexia nervosa.","location":"Syracuse, NY","website":"https://www.quadrantbiosciences.com","total_amount_raised":1339935,"total_investors":1299,"is_funded":false,"is_active":false},"key_claims":[{"claim_id":"claim-total-raised","text":"Total raised on Wefunder: 1339935","citation":"https://wefunder.com/quadrant.biosciences#claim-total-raised","provenance":{"source":"FrontCompanySummary#amount_raised","last_verified_at":"2026-06-15T05:00:18Z","as_of":"2026-06-15T22:17:57Z","confidence":"high"},"observed_at":"2026-06-15T05:00:18Z","expires_at":"2026-06-16T05:00:18Z"},{"claim_id":"claim-total-investors","text":"Total investors: 1299","citation":"https://wefunder.com/quadrant.biosciences#claim-total-investors","provenance":{"source":"FrontCompanySummary#number_of_investors","last_verified_at":"2026-06-15T05:00:18Z","as_of":"2026-06-15T22:17:57Z","confidence":"high"},"observed_at":"2026-06-15T05:00:18Z","expires_at":"2026-06-16T05:00:18Z"}],"verified_facts":[{"claim_id":"claim-total-raised","text":"Total raised on Wefunder: 1339935","citation":"https://wefunder.com/quadrant.biosciences#claim-total-raised","provenance":{"source":"FrontCompanySummary#amount_raised","last_verified_at":"2026-06-15T05:00:18Z","as_of":"2026-06-15T22:17:57Z","confidence":"high"},"observed_at":"2026-06-15T05:00:18Z","expires_at":"2026-06-16T05:00:18Z"},{"claim_id":"claim-total-investors","text":"Total investors: 1299","citation":"https://wefunder.com/quadrant.biosciences#claim-total-investors","provenance":{"source":"FrontCompanySummary#number_of_investors","last_verified_at":"2026-06-15T05:00:18Z","as_of":"2026-06-15T22:17:57Z","confidence":"high"},"observed_at":"2026-06-15T05:00:18Z","expires_at":"2026-06-16T05:00:18Z"}],"company_claims":{"tagline":"We develop novel, saliva based tests for Autism, COVID-19 and Parkinson's. ","elevator_pitch":"We develop\u0026nbsp;epigenetic saliva biomarkers including the world's first saliva test for autism. We recently received FDA emergency use authorization for a COVID-19 saliva test, and are currently working on developing tests for Parkinson's disease, concussion, and Anorexia nervosa.","story":"Leaders in the Development of Epigenetic Diagnostic ToolsQuadrant Biosciences is a life science company working with universities across the US to develop and commercialize epigenetic diagnostic solutions for autism spectrum disorder, Parkinson’s disease, and mild traumatic brain injury (concussion). Working closely with medical researchers such as SUNY Upstate Medical University and Penn State College of Medicine, we have developed a novel, saliva-based diagnostic platform called Clarifi®.In December 2019 we launched Clarifi ASD®, the world's first saliva test for autism spectrum disorder. The test, intended for children 18 months through six years of age, provides a probability of an autism diagnosis based on epigenetic markers in the saliva.Then the COVID-19 pandemic happened.Not long after we began to introduce Clarifi ASD to pediatric health care providers, the world was besieged by the COVID-19 pandemic. Our ability to access healthcare providers and share the scientific and practical utility Clarifi ASD provides to parents and physicians was greatly restricted by social distancing mandates and virus concerns which, in turn, limited our sales team’s ability to affect sales and increased commercial demand for Clarifi ASD. As a result, our sales of the Clarifi ASD test have been below expectations.So, we adapted!In response to the COVID pandemic, we immediately reduced our operating costs and, given our existing experience with RNA analysis - and the fact that COVID-19 is an RNA virus - we made the decision to pivot and work with our university partners to develop diagnostic tools for COVID-19. As a result, today we are involved in three significant, complementary COVID-19 projects to aid in the detection of COVID-19 in individuals and communities across the U.S.Watch this brief overview video of our company projects:Three Levels of Testing: A Comprehensive Approach to Assessing COVID-191. Individual Testing - Clarifi COVID-19 Test KitThe development of an individual saliva test for COVID-19 was a natural extension of our earlier work with Clarifi ASD®, which used a similar saliva collection methodology. Working in partnership with SUNY Upstate Medical University, we developed the \"Clarifi COVID-19 Test Kit by SUNY Upstate Medical and Quadrant Biosciences,\" a non-invasive and easy to administer swab that collects saliva which is then analyzed to determine the presence or absence of the SARS-CoV-2 virus. On September 22nd, we received Emergency Use Authorization (EUA) for the Clarifi COVID-19 Test Kit!The Clarifi COVID-19 Test Kit contains the saliva collection swab and the reagents needed to run the analysis and is available for use by high-complexity clinical laboratories serving patients through physicians' offices, urgent care clinics, and hospitals.2. Community/Municipal Screening: Wastewater SurveillanceThis project, funded by New York State, involves our collaboration with SUNY ESF, Upstate Medical University, Syracuse University, and global civil engineering firm Arcadis, to collect and analyze wastewater from the county and municipal sewer systems for the presence of the COVID-19 virus. Our analysis of wastewater samples provides local health officials and policymakers with early indications and information regarding the presence and preponderance of COVID-19 infections in these communities./3cb63078d5“This can be a real game-changer in the detection and monitoring of COVID-19. Information from this testing will allow municipalities to estimate COVID-19 transmission in real time, provide instant feedback on social distancing and reopening phases, help predict hospitalizations and provide confidence for locations with zero transmission to resume normal activity.”Richard Uhlig, Founder and CEO of Quadrant BiosciencesBecause this allows for large regions to be effectively tested for the presence of the COVID-19 virus, it provides a cost-effective and efficient way to screen residents in towns, cities, states, and universities, even in the absence of individual testing.3. Group/College Testing: Pooled TestingFinally, in response to an overwhelming need to efficiently test university students prior to attending classes, we have partnered with the Upstate Medical University to conduct pooled testing services for over 450,000 students preparing to begin the fall semester at SUNY schools.Each of these pooled tests for COVID-19 involves a single test of saliva samples collected from a group of 12 students. A negative test result means that all 12 students are presumed to be coronavirus-free. A positive test for the pool would mean every student in that group would need to be individually tested. Performing single tests of groups of students greatly reduces the cost of supplies, staffing, and time required to perform and interpret tests./71e98f83da\"SUNY Upstate Medical University's work with Quadrant Biosciences, a Start-Up New York company, has led to important breakthroughs in the development of saliva-based diagnostic solutions for neurological conditions such as autism spectrum disorder, Parkinson's disease and concussion injuries. The ability to transfer this innovative approach to assist colleges and universities with the unprecedented and complex work of preparing for the return of students to campuses across the state is an important part of New York's response to the COVID pandemic.\"Dr Mantosh Dewan, Interim President, SUNY Upstate Medical UniversityDisclaimers: *On September 22, 2020, The Clarifi COVID-19 Test Kit obtained Emergency User Authorization (EUA) by the Food and Drug Administration (FDA) to be used for the diagnosis fo SARS-CoV-2. The Clarifi COVID-19 test Letter of Authorization, along with the authorization Fact Sheet for Healthcare Providers, the authorized Fact Sheet for Patients and authorized labeling are available on the FDA website.The Clarifi COVID-19 Test Kit has not been FDA cleared or approved. It has been authorized by the FDA under an emergency use authorization for use by authorized laboratories. Clarifi COVID-19 has been authorized only for the detection of nucleic acid from SARS-CoV-2, not for any other viruses or pathogens, and is only authorized for the duration of the declaration that circumstances exist justifying the authorization of emergency use of in vitro diagnostic tests for detection and/or diagnosis of COVID-19 under Section 564(b)(1) of the Act, 21 U.S.C. § 360bbb-3(b)(1), unless the authorization is terminated or revoked sooner.Despite the fact that we have the expertise, capability, and customer demand for these COVID-19 tests, the supplies needed to perform quantitative PCR are becoming increasingly difficult to obtain. This, and supply chain disruptions generally throughout the industry, could impair our ability to successfully commercialize one or all of these tests.But, we are still very much an Epigenetics Diagnostic Company!The Clarifi ASD®\u0026nbsp;Test - A Game-Changer for Autism DiagnosticsWe continue to maintain a focus on our core mission to develop epigenetic diagnostic tools, such as Clarifi ASD®, the world's first saliva test for autism spectrum disorder.What is it?Clarifi ASD is a saliva test that indicates the probability that a child has autism spectrum disorder.Who is it for?Clarifi ASD is being used primarily by pediatricians and family physicians with patients (18 months through 6 years of age) with a positive autism screening test or a clinical suspicion to aid in a formal diagnosis.Why is it needed?With 1 in 54 children being diagnosed with autism in the US according to the CDC, it is one of the most commonly diagnosed developmental disabilities in the country. Unfortunately, the current diagnostic process involves long wait times, largely the result of a small number of trained clinicians to administer behavioral tests. This, in turn, leads to delays in children receiving critical intervention services. If autism is identified and treatment is initiated early, the trajectory of a child's life can be positively changed.How Clarifi ASD Can Make a DifferenceFor the first time, clinicians have an accurate biological tool to aid in the early diagnosis of autism. With this simple saliva test, Clarifi ASD can:~ Help start services earlier when treatment is most effective~ Provide specialists biological data to support their behavioral assessments~ Facilitate cost savings through improving the diagnostic process\"What we’ve been able to do over the last 7 years, working together with a very dedicated team, is develop a test that utilizes saliva and can accurately distinguish whether a child has autism spectrum disorder or does not. This relies on a new type of molecular analysis that wasn't even possible until recently.\"Frank Middleton, Ph.D. Associate Professor of Neuroscience and Physiology, Biochemistry and Molecular Biology, Pediatrics, and Psychiatry and Behavioral Sciences.When was it launched?Clarifi ASD was launched commercially in the US in 49 states (excluding New York), in December 2019.Watch a short video about Clarifi ASD here:Who we areQuadrant Biosciences Inc was started in 2015 by Founder and CEO Rich Uhlig, and we have since grown to over 40 employees. Our team has a shared passion in being a part of positive changes in healthcare. “As a company, we are committed to looking outside ourselves, and deploying our resources to assist other organizations and research efforts dedicated to improving the lives of people with autism and their families.”Richard Uhlig, Founder and CEO, Quadrant BiosciencesCapital Raised to DateAs of January 2020, we have raised over $30 million in previous financing rounds from private investors who have recognized the value in how we intend to change the landscape of diagnostics in the future.Research Grants Received To DateWe have received numerous grants to support our research efforts.*(*The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.)Quadrant Biosciences in the MediaOur company has been featured many times in national news and scientific media outlets regarding our research and technology accomplishments in the areas of autism, concussion, and Parkinson's disease.Clarifi ASD is just the Beginning! Future products in the works.One of the most exciting things that we’ve discovered is that our Clarifi epigenetic diagnostic platform has applications for many other health issues. Diagnostic solutions for early-stage Parkinson's disease, mTBI/concussion, anorexia, and schizophrenia are currently in development. Several peer-reviewed research papers have already been published on the application of this approach to these worldwide neurological health concerns.We have numerous peer-reviewed publications supporting our scienceTo date, there have been 18 peer-reviewed papers published supporting our development of epigenetic biomarkers for autism, mild traumatic brain jury, Parkinson's disease, anorexia nervosa, and Pantothenate kinase-associated neurodegeneration disease (PKAN). These have been published in a variety of scientific journals including JAMA Pediatrics, Frontiers in Genetics, Journal of Neurotrauma, Journal of Oral Microbiology, Journal of Experimental Neuroscience, and Autism Research.Research PartnershipsWe are honored to partner with a number of outstanding research universities and organizations to help further the understanding of epigenetics.International Research PartnershipsWe also actively partnered with several international research organizations:European Autism Interventions, A Multicentre Study for Developing New Medications (EU-AIMS) - first Europe-wide collaboration between organizations with the goal of identifying markers of autism that would help in earlier and more accurate diagnosis, prognosis, and the development with new therapiesComprehensive Care Center for Disability (CAID) - centers in Santiago, San Juan, Higuey and Santo Domingo, the Dominican Republic dedicated to the evaluation, diagnosis and rehabilitation of children from zero to ten years with Autism Spectrum Disorder.Our Clinical Advisory BoardOur clinical advisory board comprises some of the leading autism and epigenetic researchers and clinicians. It is our privilege to work alongside these luminaries in the field to help families and children with autism.Want to learn more?For more information about the company, download the investor deck and visit Quadrant Biosciences www.quadrantbiosciences.com; for more information about Clarifi ASD visit www.clarifiasd.com.","quick_facts":["Applied our expertise in RNA analysis to co-develop FDA authorized COVID-19 saliva test with SUNY.","Developed \u0026amp; commercialized world's first saliva based epigenetic test for autism spectrum disorder.","Sales from our new saliva COVID-19 tests have exceeded $6.5MM to date since September 2020.","We are working with NY State to test municipalities' wastewater for COVID-19.","Working with SUNY on pooled saliva surveillance of returning college students for COVID-19.","Development of Parkinson's disease, concussion, and Anorexia Nervosa, diagnostic tools in progress.","Our company is led by a former Chairman \u0026amp; CEO of Morgan Stanley Bank, 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this fund raising under Regulation A or Title III?","answer":"Hello Ram, Quadrant Biosciences is offering this as a Reg A. Thanks, The Quadrant Team"},{"question":"Hi, Your max raise goal is $15M and you stated \"Quadrant Biosciences Inc is not conducting a Regulation Crowdfunding offering.\" So this is a Reg D offering? Please clarify. Thanks.","answer":"Hello Helen, The Quadrant Team, along with the fine people at Wefunder, has spent countless hours reviewing these pages to make sure nothing has slipped through. That being said, the above stated quote, \"Quadrant Biosciences Inc is not conducting a Regulation Crowdfunding offering\" has been removed from the webpage. We are conducting a Reg A offering. Thank you for pointing this out to us and please accept our apologies. We hope to see you as an investor, The Quadrant Team"},{"question":"What valuation was given to the company in the latest funding round in Dec19?","answer":"Hello William, The valuation of the company following our last Regulation D common stock offering (December 2019) was approximately $222 Million. Please note that the shares purchased in the Regulation D offering in December are subject to 1 year holding period which is a significant liquidity restriction whereas the shares purchased through this Regulation A offering are freely transferable. We hope this explanation is helpful and that you choose to join us as an investor! Thanks, The Quadra..."},{"question":"What's the science behind testing for autism and other disease states that are primarily diagnosed through behavioral patterns?","answer":"Thank you for asking! This is game-changing technology which has been developed over the past 5 years by SUNY Upstate Medical University, the Penn State College of Medicine and Quadrant Biosciences. A quick video about our science is available here: https://vimeo.com/367101683 . Further, we’ve made a commitment to transparency in our work – our 7 peer-reviewed publications related to Autism Spectrum Disorder are available here: https://www.clarifiasd.com/our-science/ (but if you only have tim..."},{"question":"Hello ,is there any plan for future exit ( acquisition or going Public)?","answer":"This is a very savvy question – thank you. As you can likely intuit, this offering presages our intended public listing. As you may know, many of the requirements to offer securities in this Regulation A offering conform to the high standards of a public offering (i.e. financial statements audited by a PCAOB certified accounting firm); this offering will help us achieve other listing requirements as well (i.e. to list on NASDAQ, companies must also have at least 450 round lot shareholders or ..."}],"recent_posts":[{"id":142054,"entity_id":"wefunder:feed_item:142054","title":"One Day Left to Invest!","preview":"There's only one day left to invest with\u0026nbsp;Quadrant Biosciences!\u0026nbsp;Our offering closes tomorrow, February 18th. Click here to learn more.\u0026nbsp;","published_at":"2021-02-17T15:43:08Z","canonical_url":"https://wefunder.com/feed/142054"},{"id":142014,"entity_id":"wefunder:feed_item:142014","title":"Offering Closing Soon","preview":"Thursday\u0026nbsp;is the last day to invest with Quadrant Biosciences! Click here to learn about our offering.","published_at":"2021-02-16T15:34:09Z","canonical_url":"https://wefunder.com/feed/142014"},{"id":141921,"entity_id":"wefunder:feed_item:141921","title":"One Week Left to Invest","preview":"Click on the graphic above or here\u0026nbsp;to go to our Wefunder page.","published_at":"2021-02-11T23:23:51Z","canonical_url":"https://wefunder.com/feed/141921"},{"id":141877,"entity_id":"wefunder:feed_item:141877","title":"Quadrant Concussion Research in the News","preview":"Some non-COVID news for a change! Our on-going research efforts into developing a saliva test to aid the diagnosis of concussions has received some attention in the news recently.\u0026nbsp; Check out one of the recent news\u0026nbsp;stories here or click on the image below.\u0026nbsp;And don't forget the investment opportunity closes on February 18th.\u0026nbsp;\u0026nbsp;Click here to go to our Wefunder page.\u0026nbsp;","published_at":"2021-02-10T22:22:34Z","canonical_url":"https://wefunder.com/feed/141877"},{"id":141736,"entity_id":"wefunder:feed_item:141736","title":"Offering Closing Soon! A Note from CEO Rich Uhlig","preview":"Hi everyone, I hope you and your families are staying safe and healthy.\u0026nbsp;\u0026nbsp;I am writing to let you know that Quadrant Biosciences’ offering will close on February 18. My colleagues and I are grateful for your continuing support, both financial and moral, during the past year. I am proud of our team’s hard work and resilience as we successfully navigated some very challenging and unprecedented waters during this pandemic. Our prospects, particularly in relation to increased sales of ou...","published_at":"2021-02-05T21:36:23Z","canonical_url":"https://wefunder.com/feed/141736"},{"id":141650,"entity_id":"wefunder:feed_item:141650","title":"Investment Closing Soon!","preview":"We will be closing this offering later this month. Details will follow in the coming days.","published_at":"2021-02-02T20:16:58Z","canonical_url":"https://wefunder.com/feed/141650"},{"id":141600,"entity_id":"wefunder:feed_item:141600","title":"Quadrant Partners with SUNY Upstate to Build New COVID-19 Lab in Buffalo!","preview":"Exciting news!\u0026nbsp;Quadrant Biosciences and\u0026nbsp;SUNY Upstate Medical University are partnering on the\u0026nbsp;construction of\u0026nbsp;a new COVID-19 testing\u0026nbsp;lab at the University at Buffalo\u0026nbsp;to increase capacity and speed up analysis of our Clarifi\u0026nbsp;COVID-19 saliva test. The new lab,\u0026nbsp;expected to open March 1,\u0026nbsp;increases our testing capacity by 75%, potentially increasing total testing to as many as\u0026nbsp;350,000 tests per week!\u0026nbsp;The new lab will be staffed by Quadrant Bio...","published_at":"2021-02-01T19:36:42Z","canonical_url":"https://wefunder.com/feed/141600"},{"id":141502,"entity_id":"wefunder:feed_item:141502","title":"Quadrant and SUNY Upstate Project of the Year Award Update","preview":"As you may recall,\u0026nbsp;MedTech recently\u0026nbsp;named the\u0026nbsp;Clarifi COVID-19 diagnostic saliva test, co-developed by\u0026nbsp;Upstate Medical and Quadrant Biosciences,\u0026nbsp;as the 2020\u0026nbsp;Project of the Year! The honor was \"awarded to an initiative that has had a singular and demonstrable positive impact on public health.\"\u0026nbsp;In this video clip, SUNY Upstate President Dr. Mantosh Dewan and Quadrant CEO Rich Uhlig provide their thoughts about this recent\u0026nbsp;honor. Click here or on the image...","published_at":"2021-01-28T17:03:59Z","canonical_url":"https://wefunder.com/feed/141502"},{"id":140904,"entity_id":"wefunder:feed_item:140904","title":"An Interview with Rich Uhlig: \"RNA breakthroughs in autism, concussions, and COVID-19\"","preview":"Quadrant Founder and CEO Rich Uhlig was recently\u0026nbsp;interviewed on the DNA Genotek podcast \"Molecules, Microbes and Multiomics.\" The interview covered our collaboration with DNA Genotek, and\u0026nbsp;our work developing\u0026nbsp;RNA based diagnostic tools for autism, concussion and COVID-19. Check out the podcast here!As always, we appreciate the support of each and every one of our investors! If you have not yet invested, please consider joining us on this journey!","published_at":"2021-01-12T17:32:52Z","canonical_url":"https://wefunder.com/feed/140904"},{"id":140645,"entity_id":"wefunder:feed_item:140645","title":"MedTech salutes the Clarifi COVID-19 Saliva Swab as Project of theYear!","preview":"Starting the New Year off with some more great company\u0026nbsp;news!\u0026nbsp;MedTech\u0026nbsp;has\u0026nbsp;named the Upstate and Quadrant Biosciences Clarifi\u0026nbsp;COVID-19 diagnostic saliva test as Project of the Year!\u0026nbsp;\u0026nbsp;The honor is \"awarded to an initiative that has had a singular and demonstrable positive impact on public health.\" MedTech\u0026nbsp;is a\u0026nbsp;state-wide trade association of more than 100 pharmaceutical, biotech and medical technology companies, their suppliers and services providers,...","published_at":"2021-01-01T18:07:27Z","canonical_url":"https://wefunder.com/feed/140645"}],"provenance":{"source":"wefunder_public_company_profile","as_of":"2026-06-15T22:17:57Z","claims":{"total_amount_raised":{"source":"FrontCompanySummary#amount_raised","last_verified_at":"2026-06-15T05:00:18Z","as_of":"2026-06-15T22:17:57Z","confidence":"high"},"total_investors":{"source":"FrontCompanySummary#number_of_investors","last_verified_at":"2026-06-15T05:00:18Z","as_of":"2026-06-15T22:17:57Z","confidence":"high"},"active_raise_states":{"source":"Fundraise.visible(nil, nil)","last_verified_at":"2025-02-06T01:17:55Z","as_of":"2026-06-15T22:17:57Z","confidence":"high"},"latest_fundraise_state":{"source":"Fundraise.visible(nil, nil).order(funding_started_at)","last_verified_at":"2025-02-06T01:17:55Z","as_of":"2026-06-15T22:17:57Z","confidence":"medium"}}}}}}