# MIT research validates JOGO's mechanism of action, confirming that muscle activity promotes neuron growth | JOGO Health

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- Entity ID: wefunder:feed_item:177544
- Published at: 2024-11-16 22:53:01 UTC
- Updated at: 2025-07-16 19:57:25 UTC

## Author
Siva Nadarajah

## Subject
JOGO Health

## Content
A recent study published by the Massachusetts Institute of Technology (MIT) validates JOGO's mechanism of action: when muscles exercise, they help neurons grow.JOGO enables even the body’s tiniest skeletal muscles to "properly" exercise, something regular physical therapy or standard exercise often cannot achieve.MIT researchers discovered that neurons respond not only to the biochemical signals of exercise but also to its physical impacts. The team observed that when neurons are repeatedly stretched and compressed—similar to how muscles contract and expand during exercise—they grow as much as they do when exposed to a muscle’s myokines.Think of JOGO versus general physical therapy as "targeted cancer therapy" versus broader chemotherapy. While physical therapy and standard exercise help neurons grow, they don’t always target the specific neurons needed to address a particular condition. JOGO, on the other hand, targets specific muscles and their corresponding neurons at precisely the right dosage.For someone recovering from a stroke, simply exercising might be impossible. But with JOGO, even small muscle movements can stimulate corresponding neurons in the brain to grow. Additionally, JOGO can measure muscle fatigue to ensure that the exercises are safe and do not cause muscle damage.You can read the full research here:MIT News: When Muscles Work Out, They Help Neurons Grow