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Influenza H5N1, a.k.a. \"bird flu,\" normally infects wild birds (such as ducks, geese, etc.) and farmed chickens, but does not normally infect mammals, including humans. However, there have been a couple of outbreaks of H5N1 among humans in the recent past. H5N1 originated in Hong Kong in 1997, and has caus...","published_at":"2024-04-22T20:05:18Z","canonical_url":"https://wefunder.com/feed/172797"},{"id":172242,"entity_id":"wefunder:feed_item:172242","type":"FeedItem::Update","title":"InvVax makes it first foray into cancer!","preview":"I'm excited to announce that we've expanded our pipeline into cancer! This will be very early-stage R\u0026D. As a graduate student (yes, over 20 years ago), I had an idea to treat cancer by exploiting a universal feature of all cancers, which is the aberrant regulation of the Rb-E2F pathway. (This was the main topic of my PhD research.) E2F is a protein that drives cells into DNA replication, and Rb restrains E2F. Thus, E2F is the \"gatekeeper\" that determines whether a cell divides or not, and Rb...","published_at":"2024-04-05T18:40:35Z","canonical_url":"https://wefunder.com/feed/172242"},{"id":171398,"entity_id":"wefunder:feed_item:171398","type":"FeedItem::Update","title":"Critical comparison of optimal flu vaccine modality","preview":"Greetings everyone,We're happy to say that our pivotal flu vaccine mouse study with Duke University is underway! Funded by an NIH grant through the Duke CIVICs program (Collaborative Influenza Vaccine Innovation Centers), we're comparing our adenoviral-vectored flu vaccine, already proven to work well, to mRNA as well as to peptides. As you almost certainly know, mRNA was the difference-maker that got the COVID-19 vaccine into clinics and played a major role in ending the pandemic. Many compa...","published_at":"2024-03-08T22:30:42Z","canonical_url":"https://wefunder.com/feed/171398"},{"id":171251,"entity_id":"wefunder:feed_item:171251","type":"FeedItem::Update","title":"A new modality: Antibodies as prevention","preview":"Announcing solid progress toward our goal!Hello everyone,We're pleased to report substantial progress on our stable prophylactic antibodies (spAbs) work!As you might know, we received funding from the National Science Foundation just over two years ago to work on a project which is only tangentially related to our vaccine work, but is arguably the most exciting work in our pipeline. Namely, we are designing an antibody (Ab) backbone that is so extremely stable that our Abs can be given prophy...","published_at":"2024-03-02T19:18:59Z","canonical_url":"https://wefunder.com/feed/171251"},{"id":170436,"entity_id":"wefunder:feed_item:170436","type":"FeedItem::Update","title":"New COVID-19 Vaccine is Subpar","preview":"The news is out\u0026nbsp;- this year's COVID-19 vaccine is just 54% effective:\u0026nbsp;https://www.statnews.com/2024/02/01/updated-covid-vaccine-effectiveness/That puts it in the range of the annual flu shot, which averages 40% effectiveness, at times is as high as 60%, and sometimes is as low as 20%. What does that mean, from a mathematical standpoint? (As an aside, you might hear the word \"effectiveness\" on occasion and other times, \"efficacy.\" The former is more a measure of natural world data, w...","published_at":"2024-02-08T18:43:55Z","canonical_url":"https://wefunder.com/feed/170436"},{"id":170186,"entity_id":"wefunder:feed_item:170186","type":"FeedItem::Update","title":"KingsCrowd Capital's Investment into InvVax","preview":"Hello everyone,I'm excited to share some groundbreaking news with our InvVax community. KingsCrowd Capital has made a solid investment in InvVax during our current Wefunder round, and we've been awarded a stellar 4.3 rating on their platform. This is a monumental endorsement of our work and vision at InvVax.Understanding KingsCrowd CapitalKingsCrowd Capital is at the forefront of equity crowdfunding analysis, providing independent, AI-powered ratings and analytics for the online private marke...","published_at":"2024-01-24T18:55:28Z","canonical_url":"https://wefunder.com/feed/170186"},{"id":170038,"entity_id":"wefunder:feed_item:170038","type":"FeedItem::Update","title":"InvVax Video Update","preview":"Hi everyone,I'm thrilled to share a recent video interview that highlights the innovative work we're undertaking at InvVax. This conversation is an engaging overview of our mission and the exciting investment opportunity available to those who wish to join us in this groundbreaking venture.In the video, you'll hear about our unique approach at InvVax - tackling the challenge of rapidly mutating viruses like influenza and COVID-19. We focus on developing vaccines that target crucial, unchangea...","published_at":"2024-01-17T20:54:10Z","canonical_url":"https://wefunder.com/feed/170038"},{"id":169830,"entity_id":"wefunder:feed_item:169830","type":"FeedItem::Update","title":"InvVax's Year in Review: Pioneering Partnerships, Innovative Research, and Grant Triumphs in 2023","preview":"Hello Everyone,As we step into a new year, I want to share a personal reflection on the significant milestones and progress we've made at InvVax in 2023. It's been a year of growth, discovery, and collaboration, and I'm proud to recount these highlights with you.Firstly, we welcomed Nima Shiva, MBA, as our new Head of Business Development. Nima's impressive background, with a Bachelor’s in Neuroscience and Physiology from the University of California, San Diego, and an MBA from the Marshall S...","published_at":"2024-01-09T19:06:36Z","canonical_url":"https://wefunder.com/feed/169830"},{"id":169726,"entity_id":"wefunder:feed_item:169726","type":"FeedItem::Update","title":"Elevating Impact in Global Health Innovation","preview":"It is very difficult, in this season of gladness and joy, to share with you this tragic story of a beautiful young girl, fully healthy, who perished just one day after being diagnosed with the flu.Read Article at Today.comStories like these are a sober reminder – indeed, a spark lit under me –motivating me to work double overtime to make the InvVax product a commercial reality. If there is a girl like Teresa, there are 650,000 more who succumb each year to the flu worldwide; and what is my ti...","published_at":"2023-12-29T19:55:36Z","canonical_url":"https://wefunder.com/feed/169726"},{"id":169104,"entity_id":"wefunder:feed_item:169104","type":"FeedItem::Update","title":"Exciting Update: InvVax Early Bird Opportunity Extended!","preview":"Hello Everyone!I hope this message finds you well. I'm thrilled to share some exciting news with you regarding our ongoing Wefunder campaign.As many of you know, we launched our campaign with an early bird offer that has garnered significant interest and support. 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